Selection of accelerator production routes of 67Cu
Sandor Takacs
Institute for Nuclear Research, Hungarian Academy of Sciences
Poster
No conflicts.
The 67Cu has proper theranostic decay characteristics. The 70Zn(p,a), 68Zn(p,2p), 70Zn(d,an), 68Zn(d,2pn), 67Zn(d,2p), 64Ni(a,p), 65Cu(a,2p), and 71Ga(p,an) production routes were studied. To compare the different production routes a calculation tool was developed to predict the number of atoms and/or the activity of the produced radionuclides in the irradiated target. It includes both the direct and decay production of the main and the side reaction products. Accumulation of long lived radionuclides in the target material such as 65Zn is also estimated.
The number of atoms and their corresponding activity produced during the irradiation is calculated as function of bombarding energy, irradiation and cooling time. For several of the reactions no experimental data are available therefore their excitation functions were taken from the TENDL-2017 data library. The (p,a) and (d,an) reaction on 70Zn provide the cleanest 67Cu. Taking the 70Zn(p,a)67Cu reaction as an example. The EOB activity of the produced 67Cu radioisotope can reach about 37GBq (1Ci) by running the irradiation for 24h with 300microA proton beam on a 98% enriched 70Zn target.