Indigenous development of Semi-Automated Solid target irradiation assembly compatible with PETtrace-800
Kanchan Kushwaha a, b,1, Pravind Maletha a, Sunil Kamble c, Jyothish Babu c, Tejindar Singh Sabharwal c, Kavindra Pathak c, Manish Kumar c, Nand Kishore Prasad c, Tushar Kanti Saha c, Sharmila Banerjee a, b
a. Radiation Medicine Centre, BARC, TMH Annexe, Parel, Mumbai 400012, India b. Homi Bhabha National Institute, BARC, Anushakti Nagar, Mumbai 400094, India c. Technical Physics Division, BARC, Trombay, Mumbai 400085, India
Poster
No potential conflict of interest relevant to this abstract was reported.
Introduction
64Cu has been known to be an effective radioisotope particularly in PET imaging studies. A solid target assembly for the production of 64Cu via 64Ni (p, n)64Cu has been developed in-house in order to extend the utilization of the existing PETtrace-800 facility.
Materials and Method
Considering the compatibility requirements, the design was developed (fig-1). 16.5 MeV proton beam is allowed to sequentially incident on Havar foil, attenuation foil and 64Ni layer electroplated on base plate. Helium gas and water were used for heat dissipation (fig-2, table-1). The assembly body is made of aluminium and copper. Removal of base plate is carried out using semi-automation procedure. Stepper motor moves the base plate in horizontal direction and drops it in lead pot through a pipe, which will be carried out manually for chemical processing.
Results and Conclusions The use of Solid target assembly as described has been successfully demonstrated in the PETtrace-800 facility using proton beam of 2 µA for 30 m1. Further studies using higher beam current are under progress.
Reference
1)Production of 64Cu, using indigenously developed solid target assembly in Medical Cyclotron Facility in Radiation Medicine Centre (ESRR’18 – 19th Eur. Symp. Radiopharmacy Radiopharm. Apr 5-8,2018)